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The manufacture of Busulfan API (CAS No. 55-98-1) is concentrated within multiple Indian pharmaceutical hubs. Specifically, organizations in locations like Gujarat, Tamil Nadu, and Telangana are emerging players. Prominent manufacturers including A, Y, and Company 3 have established facilities capable of producing substantial quantities of this critical antineoplastic API. Present funding in infrastructure and modern fabrication processes are expected to improve India's position as a international supplier of Busulfan.